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MycoFold™ rHu Interleukin 2 (IL-2)

GR1004-10

Species Reactivity
Human,Mouse

Purity
≥ 98%

Stability
See data comparison

Synonyms and Aliases
IL 2, IL2, IL-2, interleukin 2, T cell growth factor, TCGF, lymphokine

MycoFold™ rHu Interleukin 2 (IL-2)

Description

MycoFold's Recombinant Human Interleukin 2 (rHu IL-2) protein is a single-chain, approximately 15.3 kDa (monomer), non-glycosylated lymphokine secreted from P. pastoris yeast.  Lyophilized protein is tested for specific activity, purity, endotoxin, host cell protein/DNA, and mycoplasma, and priced for industry-leading bioactivity value (IUs/mg/$).  Chaperone-guided folding and engineered secretion pathways generate native tertiary 3D structures, resulting in optimized specific activity and thermal stability.

Product Features

Protein Features
  • Carrier protein-free formulation
  • Excludes affinity tags
  • Accurate mass and activity control
  • High purity confirmed by Mass Spec (≥ 98%)
Manufacturing Process
  • Animal free yeast expression system
  • Multi-step, tagless downstream purification strategy
  • Sterile microfiltration and aseptic filling/lyophilization
Shipping / Reconstitution
  • Shipped at ambient temperature
  • Initially reconstitute in deionized water to 0.3 - 0.5 mg/mL.
  • Avoid repeated freeze-thaw cycles.
For Use Statement

For research applications only. This product is intended to be used as ancillary materials and not for unauthorized commercial or therapeutic uses.

Application Resources

Documentation

Release Testing

  • Biological Activity (dose-dependent proliferation of HT-2 clone (A5E) cells against NIBSC 86/500).
  • Specific Activity (dose-dependent proliferation of HT-2 clone (A5E) cells against NIBSC 86/500).
  • Molecular Mass (MALDI-TOF)
  • Purity (SDS-PAGE)
  • Endotoxin (USP<85>)
  • Sterility (USP<71>)
  • Appearance (Visual inspection)
  • pH (USP<791>)

Functional Data

FAQs